Research topics
Source-linked introductions to peptide synthesis, analytical quality, stability, delivery and molecular design.
Peptide Therapeutics: From Sequence Design to Developability
A practical view of why peptides occupy a useful space between small molecules and larger biologics, and which design constraints shape viable research candidates.
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Fmoc Solid-Phase Peptide Synthesis: Workflow and Control Points
How iterative deprotection and coupling build peptide chains on resin, and where sequence-dependent side reactions, incomplete conversion and purification burden enter the workflow.
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Reference Standards and the Quality of Synthetic Peptides
Why a peptide reference standard needs documented identity, assigned content and stability rather than serving as an unqualified comparison sample.
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Peptide Stability in Aqueous Formulations
A research-oriented map of chemical and physical degradation pathways, formulation variables and stability-indicating measurements for peptides in solution.
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Cyclic Peptides: Conformation, Permeability and Design Space
Cyclization can constrain peptide conformation and reshape stability, target engagement and permeability, but its effects depend on ring architecture rather than the label alone.
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Cell-Penetrating Peptides as Delivery Tools
Cell-penetrating peptides can associate with molecular cargo and influence uptake, but delivery claims require evidence for internalization, release and biological availability.
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Antimicrobial Peptides: Sequence, Membrane Interaction and Assay Design
Antimicrobial peptides span diverse structures and mechanisms; interpretable studies separate direct microbial effects from membrane damage, assay conditions and host-cell compatibility.
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Peptide-Drug Conjugates: Targeting, Linkers and Payload Release
A peptide-drug conjugate is a coordinated system in which the targeting sequence, linker, payload and release mechanism must be evaluated together.
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Oral Delivery of Peptides: Barriers and Experimental Strategies
Oral peptide delivery research must address enzymatic degradation, low epithelial permeability, variable gastrointestinal conditions and the gap between uptake and useful exposure.
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Extending Peptide Half-Life: Mechanisms and Tradeoffs
Chemical modification and carrier interactions can slow clearance or proteolysis, but every half-life strategy may also alter potency, distribution, aggregation or analytical complexity.
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Self-Assembling Peptides as Programmable Biomaterials
Short peptide building blocks can organize into fibers, sheets and gels, connecting sequence-level interactions with material-scale mechanics and presentation.
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Cyclic Peptide Libraries and Phage Display Selection
Genetically encoded libraries can explore large cyclic-peptide sequence spaces, but library quality, selection pressure and enrichment artifacts determine what a screen can reveal.
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